Disorders of haemostasis in clinical practice

Haemostasis is one of the mechanisms that maintains the integrity of the internal environment. Disruption of the homeostatic balance can result in a bleeding state on the one hand, and a thrombophilic state on the other. Given the mortality of thrombosis and embolism, these are feared pathological conditions, and anticoagulant and antithrombotic therapy is key in many medical fields. These drugs are among the most prescribed, yet doctors may still have concerns about their side effects and drug interactions. However, bleeding conditions, whether from vascular (purpura) or platelet causes, are also feared. Haemostatic disorders most often develop in hospitalised patients, but general practitioners and outpatient doctors may also encounter the first symptoms and should be able to diagnose them in a timely manner.

This monograph by the experienced author, Associate Professor Petr Dulíček, is sufficiently detailed, yet practically and clinically focused, without overwhelming the reader with superfluous theoretical details. It provides good orientation in practice and is a useful source of information for undergraduate and postgraduate education.
It is useful for internists, surgeons, intensivists, gynaecologists and obstetricians, cardiologists, haematologists, as well as general practitioners, medical students, and workers in biochemical laboratories.