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Dodging fast-moving cars, crazy taxi drivers, open doors, and eight million grumpy pedestrians is the daily bread of Wilee (Joseph Gordon-Levitt), New York' s best agile and penetrating cyclo-messenger.

It wants special training to ride on fixie - super light bikes in one gear, without brakes and between riders, who are less able cyclists and suicidal idiots, who risk it there will be a greasy stain on the sidewalk every time, when they take to the streets. But a guy who is used to exposing his life to such danger gets into a situation he is not used to either.

During a routine delivery, his life turns into a chase for life and death that takes place on the streets of Manhattan. As Wilee picks up her last envelope during the day, she discovers that this package is different. This time, someone is really trying to kill him.